Sacred Journeys: Psychedelics and the Search for Meaning

Betty Brandt • August 8, 2025

Spirituality and Psychedelics

I spent several decades of my adult life as a practicing Marriage & Family Therapist. In all those years, I encountered a handful of people whose depressive symptoms had such a hold on them, they were immobilized. It seemed that no treatments were available to help them enjoy life again.


Today, the medical use of psychedelics is adding a powerful option. Much research is being done in this field, with quite astounding results. There are a growing number of places in Indianapolis where people suffering from depression can take psychedelics in the presence of trained therapeutic practitioners.


Now, research is expanding into the field of spirituality and psychedelics. The best-known study is a 2016 collaboration between Johns Hopkins and NYU Schools of Medicine, involving 22 religious leaders—Episcopalian, Presbyterian, Methodist, Lutheran, United Church of Christ, Congregational, Baptist, Eastern Orthodox, Pentecostal, Reformed Church in America, Roman Catholic, Unitarian Universalist, Orthodox Jew, Reconstructionist Jew, Renewal Jew, Sunni Muslim, and Zen Buddhist.


The results, which were delayed for almost a decade, are now available. They reveal that 96% of the participants retroactively rated their psilocybin experience among the top five most spiritually significant, profoundly sacred, psychologically insightful, and meaningful experiences of their lives.


Some came to see all religions as part of one truth, while many felt more grounded in their personal traditions. Some attributed their psychedelic experiences entirely to God, while others credited chemical changes in their brains. They reported positive changes in their effectiveness as religious leaders, as well as in their non-religious attitudes, moods, and behaviors.


Are we on the cusp of a dramatic change in the acceptance of psychedelics beyond medical uses?


The American Indian Religious Freedom Act of 1978 safeguards the use, possession, and transportation of peyote by Indigenous people for bona fide traditional ceremonial purposes. Now, a non-Indigenous group in Utah has sued—and won—their case.


On August 4, 2025, District Judge Jill Parrish of the U.S. District Court of Utah ruled in favor of a religious group called Singularism, which had sued for the right to use psychedelic mushrooms in their worship services as a conduit to profound spiritual experiences. Judge Parrish sided with the group.


Just two days later, on August 6, 2025, Rabbi Jay Michaelson spoke at a Spirit and Place event in Indianapolis. Rabbi Michaelson is a field scholar at the Emory Center for Psychedelics and Spirituality and a fellow at Harvard Law School’s Project on Psychedelic Use, Law, and Spiritual Experience (PULSE).


In March 2025, he co-organized the first-ever conference on the legal recognition of religious psychedelic use in Christian, Jewish, and Muslim communities. His colleague, Gary Laderman—a religion scholar at Emory University—has a book titled Sacred Drugs: How Psychoactive Substances Mix with Religious Life, coming out in September 2025. These two men are leaders in this emerging field of spirituality and psychedelics.


I have lots of questions. Maybe you do too.


Are we approaching a time when psychedelics will be welcomed into the spiritual practices of American faith traditions? If so, how long until that door opens?


Would I be willing to take part in a religious ceremony using psychedelics? Would you?


How would such an experience transform my spiritual life?


Could clergy take part in a psychedelic experience as part of their seminary training?


Do seminaries need to train religious leaders to provide care and guidance to those in their congregations who want to process their psychedelic experiences?


A whole new opportunity for spiritual growth is opening before us. Are we ready?

By Matthew Vire February 17, 2026
The Garden welcomes Josh Riddick for a message on justice, faith, and how Jesus’ desert journey offers courage and clarity for our moment.
By Rev. Richard Brendan February 9, 2026
To Be Known, Chosen, and Loved
February 3, 2026
A powerful call to action from a local vigil: “Never Again” is now. Stand up for dignity, justice, and immigrant rights in Indianapolis.
February 2, 2026
With The Universal Christ , Richard Rohr presents a vision of Christ not as a figure confined to Jesus alone or to Christianity, but as the eternal, cosmic presence of God permeating all creation from the beginning. Rohr distinguishes between Jesus (the historical person) and Christ (the divine reality revealed through Jesus). He argues that Jesus is the “first incarnation,” present in every person, place, and particle of the universe. Drawing on Scripture—especially John 1, Colossians 1, and Paul—along with early Christian mystics and contemporary science, Rohr reframes salvation. Rather than describing it as rescue from a fallen world, he presents salvation as awakening to the divine presence already within and among us. This universal, incarnational vision invites a way of life grounded in compassion, solidarity with suffering, and participation in the healing and transformation of the whole world. Rohr’s approach also offers a theological grounding that aligns with The Garden’s emphasis on finding the sacred in the ordinary and celebrating a universal spiritual nature. Come explore this with us Sunday at The Garden.
By Betty Brandt February 2, 2026
A stirring reflection on the Black National Anthem’s enduring message of hope, unity, and the pursuit of freedom—honoring Black History Month through song and story.
By Betty Brandt January 29, 2026
Reflections on a community celebration honoring Rev. Martin Luther King Jr., with powerful storytelling, music, and recognition of local justice work, hosted by northside Indianapolis Shalom Zone churches.
By Betty Brandt January 29, 2026
A gentle reflection on the spiritual practice of stillness—inviting readers to pause, notice, and embrace the quiet beauty of going nowhere during Lent.
By Betty Brandt January 27, 2026
Learning to Greet the Day With Wonder
By Rev. Dr. Carolyn Scanlan-Holmes January 27, 2026
As February 2nd approaches, we find ourselves reflecting on Groundhog Day—a moment filled with anticipation and hope. Just like that furry little creature who predicts the end of winter, we often face our own shadows and uncertainties. Are you tired of the cold and darkness, yearning for the warmth of spring? Maybe you’ve felt stuck in a season that just won’t seem to shift, repeating the same patterns and wondering when change will come. This Sunday, we’ll explore how to step forth in faith amidst life's challenges, seeking light and renewal even when the world feels overwhelming. Come as you are, and let’s lean into transformation together. Don't miss this opportunity to gather in community and discover ways to embrace hope and resilience! See you there!
By Rev. Dr. Carolyn Scanlan-Holmes January 20, 2026
In elementary school, we learn the life-saving phrase “stop, drop, and roll.” It’s a simple yet powerful reminder that can literally save lives. This phrase resonates with me when I reflect on Jesus’ call to his first disciples. He calls these fishermen right in the midst of their daily routines to stop everything and embark on a mission that would transform their lives forever. This Sunday, let’s take a moment to pause and consider what could happen if we were to stop, drop our distractions, and enroll in the invitation to live our best lives. Join us as we explore how answering this call can ignite a profound change within us!